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What is the cause of erythema multiforme ?

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 ERYTHEMA MULTIFORME : Erythema multiforme  ( EM ) is a  skin condition  that appears with  red  patches evolving into target lesions typically on both hands. It is a type of  erythema  possibly mediated by deposition of  immune complexes  (mostly  IgM -bound complexes) in the superficial  microvasculature  of the skin and  oral mucous membrane  that usually follows an infection or drug exposure. It is an uncommon disorder, with peak incidence in the second and third decades of life. The disorder has various forms or presentations, which its name reflects ( multiforme , " multiform ", from  multi-  +  formis ). Target lesions  are a typical manifestation. Two types, one mild to moderate and one severe, are recognized ( erythema multiforme minor  and  erythema multiforme major ). Erythema multiforme was first described by von Hebra in 1860. Erythema multiforme is an immune-mediat...

What is Erythema multiforme ?

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 Erythema Multiforme  Erythema multiforme is a skin reactions that can be triggered by an infection or some medicine . Its usually mild and goes away in a few weeks . There also a rare , severe  form that can affect the mouth , gentials and eyes and can be life - threatening. This is known as erythema multiforme major . Erythema multiform is an immune - mediated , typically self- limiting , mucocutaneous condition charactertised by target lesions. Significant  mocosal involvement distinguishes erythema  multiforme major from multiform minor. Episode can be isolated , recurrent , or persistent .  In most cases , erythema multiforme is precipitated by herpes  simplex virus {HSV } infection , alternative  trigger include  other infections , medications, and vaccinations. Classic  target  lesion present as concentric rings of color  variation which  develop symmetrically in an acral distribution , with or without involvement o...