Posts

Showing posts with the label bullous

How aggressive is acral lentigious melanoma ?

Image
  ACRAL LENTIGINOUS MELANOMA : The word “lentiginous” means that the spot of melanoma is much darker than the surrounding skin. It also has a sharp border between the dark skin and the lighter skin around it. This contrast in color is one of the most noticeable symptoms of this type of melanoma.  Acral lentiginous melanoma (ALM) is a type of malignant melanoma. Malignant melanoma is a form of skin cancer that happens when the skin cells called melanocytes become cancerous. Melanocytes contain your skin color (known as melanin or pigment). In this type of melanoma, the word “acral” refers to the occurrence of the melanoma on the palms or soles. ALM is the most common type of melanoma in people with darker skin and those of Asian descent. However, it can be seen in all skin types. ALM may be hard to recognize at first, when the patch of darkened skin is small and looks like little more than a stain or bruise. Early diagnosis and treatment are essential. What are the sign and sym...

What is junctional epidermolysis bullosa dermnet ?

Image
 JUNCTIONAL EPIDERMOLYSIS BULLOSA : Junctional epidermolysis bullosa (JEB) is characterized by fragility of the skin and mucous membranes, manifest by blistering with little or no trauma. Blistering may be severe and granulation tissue can form on the skin around the oral and nasal cavities, fingers and toes, and internally around the upper airway. Blisters generally heal with no significant scarring. Broad classification of JEB includes JEB generalized severe and JEB generalized intermediate. In JEB generalized severe, blisters are present at birth or become apparent in the neonatal period. Congenital malformations of the urinary tract and bladder may also occur. In JEB generalized intermediate, the  phenotype  may be mild with blistering localized to hands, feet, knees, and elbows with or without renal or ureteral involvement. Some individuals never blister after the newborn period. Additional features shared by JEB and the other major forms of epidermolysis bullosa (EB...