How is lobomucosis treated ?

LOBOMUCOSIS :

Lobomycosis is a fungal infection of the skin. It usually presents  with bumps in the skin, firm  swellings  deep skin lesions , or malignant tumors . It is caused  by lacazia loboi . Transmission is generally by  direct contact with contaminated water, soil , vegetation , or by direct contact  with an infected dolphine . This disease is usually found in humans and bottlenose dolphine with the possible risk of transmission from one species to the other .



This disease is usually found in humans  and  bottlenose dolphins with the possible  risk of transmission from one species to the other . It was discovered by Brazillian dermatologist Jorge Lobo . Other names which were given to the disease are keloidal Amazonian blastomycosis, blastomycoid granuloma , miraip and piraip . These last two 2 names were given by natives of the Amazon and mean that which burns .

WHAT ARE THE SIGN AND SYMPTOMS OF LOBOMUCOSIS ?

 The disease is endemic in rural  regions  in South  American  and Central America . Infection most commonly develops after minor  scratches or insect bites , but many  trauma . patients  cannot recall any skin  trauma . Human to human transmission does not occur , and the disease is only acquired from the environment . The disease is only acquired  from  the environment . The disease  manifests as chronic keloidal nodular lesions on the ears , legs or arms . 



Diagnosis of Lob's disease is made by taking a sample of the infected skin and examining it under the microscope . The cells appear to be yeast like with a diameter of 5 to 12 . Attempts to culture L. loboi have so far been unsuccessful . 

WHAT ARE THE CAUSES OF LOBOMUCOSIS ?

Lobomycosis is caused by Lacazia loboi . The organism is an uncultivable dimorphic onygenales  fungus that is found in water , soil , and vegetation . It is thought that traumatic implantation  of the fungus into the dermis is the most likely mode of transmission . Lobomycosis  does not appear to spread  through human to human transmission . 



HOW TO TREAT LOBOMUCOSIS ?

Surgical  excision or cryosurgery  is the treatment of choice . Treatment with antifungaln has been considered ineffective , but the use of  clofazimine and dapsone in patients with leprosy and lobomycosis has been found to improve the latter . This treatment regimen , with concomitant itraconazole , has been used to prevent recurrence after surgery .

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